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Clay Siegall develops niche market for Seattle Genetics

Despite dramatic improvements in the survival rates of almost all types of cancer between the turn of the 20th century in the mid-twentieth century, many types of cancer have not seen dramatic improvements since then. This is largely due to the fact that most of the major breakthroughs in cancer treatment happened between the 1930s and the 1960s. Today, that is beginning to change. However, prior to the year 2000, the three main pillars of cancer treatment, surgery, radiation and chemotherapy, were the same ones that had existed since the 1930s and 40s.

It was with this in mind that a senior researcher at Bristol-Myers Squibb named Clay Siegall decided to branch out on his own, concentrating on developing novel treatments for some of the cancer types that had not seen significant mortality improvements over the preceding 50 years. By 1998, the year in which Dr. Siegall founded Seattle Genetics, he had been working as a top cancer researcher for more than 15 years. He had decided in college that he wanted to pursue a career in cancer research when one of his family members got sick with cancer. Although they eventually pulled through, they nearly died at one point, not due to the disease itself but due to the development of severe anemia secondary to the chemotherapeutic regime that was necessary to treat it. This made Dr. Siegall realize that there must be a better way to go about fighting this horrible disease.

Upon founding Seattle Genetics, Dr. Siegall decided that he would not follow the same strategies as other pharmaceutical companies. After all, they had huge economies of scale and already had large portions of their market completely cornered. Instead, Dr. Siegall decided to go after areas which had been largely neglected and in which little progress had been made over the prior decades. One such area was the disease called non-Hodgkins lymphoma.

Dr. Siegall began developing a drug called ADCetris, an antibody drug conjugate that was specifically designed for the treatment of non-Hodgkin’s lymphoma. It eventually became the first FDA-approved antibody drug conjugate, saving the lives of thousands of patients and propelling Seattle Genetics into the realm of major pharmaceutical players.

Goettl Completes Big California Purchase

For people that are located in the southwest United States, which are prone to very hot summer months, having a quality HVAC system in place is very important. Along with having a good HVAC system, you also need to have a good repair service to help fix the system when the time comes. For those that are in the southern California area, a regional HVAC service provider should soon be growing in the market place.

Over the past few weeks, Goettl Air Conditioning bought one of the top local HVAC firms, Walton’s Heating and Air. Goettl Air Conditioning is one of the leading providers of HVAC installation and management systems in the southwest United States. The company has been in business for over 50 years and has a strong presence in a number of top cities including Phoenix, Las Vegas, and other areas of Utah and Arizona. The current sale of the Walton’s should give Goettl Air Conditioning a larger market share in the Los Angeles and San Diego markets as well.

The sale of Walton’s came after a two-year negotiation for the sale of the company. Goettl Air Conditioning was very interested in buying the company due to their strong reputation for service and quality. Walton’s also has a long list of commercial clients, which can provide a more profitable and consistent base of revenue. The purchase of Walton’s should help to make Goettl one of the largest such companies in this area of the country. Prior to the purchase of the company, Goettl had over 300 employees. With the acquisition, this could come closer to 500 people.

The CEO of Goettl Air Conditioning, Ken Goodrich, stated that they expect to make further acquisitions in coming years. The company has stated that they would like to become a regional brand and eventually expand to warmer markets all over the country. By the end of 2018, the company plans to expand into some select cities in Northern California, Texas, and parts of New Mexico.

Mortgaged expert Todd Lubar and the Spread of Smart Home Technology

The modest and high tech features of smart homes have created a competitive edge in real estate because they optimize home living. Through transmission technologies like Wi-Fi and Bluetooth homeowners can control and monitor automated devices around their homes. Real estate developers are quickly embracing these concepts because of the rising vibrant and knowledgeable market.

Smart tech innovators like Apple and Amazon have made a huge impact on smart home industry with their intelligent virtual personal assistants Siri and Alexa, who obey voice commands on smart appliances that have been synchronized. Check out Medium to know more.

According to Patch, several real estate companies like Quadrant Homes in Bellevue, Washington have incorporated smart home innovations as a standard feature in all their new housing projects. The city of Seattle which has set the trail blazer for smart home technology, houses the biggest population of homeowners with inkling towards smart technology. The rate at which the smart home innovations are spreading across states is a glimpse of how the rural areas will be in the next decade. It has been projected by TechSci Research that by 2021, global smart home market will exceed $60 billion and this is the right opportunity to invest in smart home market because soon this lucrative venture will be the norm in just a matter of time.

Some of the smart home features include:

  • Nest thermostat that regulate home temperatures
  • Ring-motion detection doorbells
  • Caseta Wireless programmable lighting systems
  • Hub systems that allow homeowners to issue commands using hidden microphones
  • Force detecting floors that detect mobility problems in seniors
  • Lutron automated window shades

Smart homes benefits:

  • Safety and security
  •  Convenience
  • Smart toilets that detect health problems by analysing stool and urine samples then send reports to a doctor.
  • Provide continued independence for the elderly and handicapped boosting their esteem and confidence greatly.

Smart homes challenges:

  • Cost of installation makes the houses pricier because of the high tech equipment.
  • Security breaches when the systems are infiltrated by hackers exposing owners to potential risk.
  • Difficulty convincing the senior population who are more guarded and wary compared to the younger population.
  • The artificial intelligence to comprehend all languages and accents is still very limited.

About Todd Lubar

He is a passionate real estate developer with a vested interest in smart homes. Todd Lubar is currently the President of Global Ventures, LLC and also serves as the Vice President of Legendary Investments. With over two decades of experience in real estate, Todd has consistently been ranked among top 25 mortgage originators in the U.S.

Besides real estate, Todd has also worked in the entertainment industry, recycling and demolition industries. He is also greatly vested in helping people dreams of owning their homes by lending loans to them. Click here to follow Todd:

Dr. Walden is Getting What She Wants

Dr. Jennifer Walden is woman who is known as an expert plastic surgeon Dr. Jennifer Walden was born and raised in Austin Texas. She graduated from the University of Texas, and she began to work at the Manhattan Ear, Nose, Eyes and Throat Hospital. She first went to school to be an anesthesia doctor, but she later grew to have a deep interest in plastic surgery. Walden grew to love her life in the big city, and started up a practice in New York.

There are a few female doctors who work as plastic surgeons because plastic surgery requires extended schooling. Women who decide to go into plastic surgery have to delay their childbearing years in order to finish up all of their training. Few female doctors wish to do that. Dr. Walden stands in a class of her own because she was able to become a world-renowned plastic surgeon, and she was also able to start a family. Click here to know more.

Walden made the choice to become a single parent because she knew that she did not want to have to sacrifice a family for her career. Walden decided that she was going to have a family in her late 30s, so she got in vitro fertilization, and she became pregnant with her two boys. Walden wanted to be able to raise her family close to where she grew up, so she moved her entire practice to Austin Texas.

Dr Jennifer Walden Reviews is a plastic surgeon who has been featured in many of the most popular magazines in the US. Apart from that, she has also been an expert doctor on a variety of television programs. Dr. Walden is an expert in rhinoplasty, Liposuction, breast augmentation, and eye lifts. Dr. Walden is a woman who knows what she wants, and she has never let anything get in the way of her dreams. Dr Walden on YouTube.

Who Is Paul Mampilly And How Does He Guide Investors?

Paul Mampilly is one of the most-respected people on Wall Street, and he has been guiding investors for many years. He recently gave an interview where he talked about principles of business that he is interested in, and he knows that there are a number of people who will benefit quite a lot of from his services. This article explains how Paul is serving clients, and it gives an idea of how he may help someone reach their goals.

#1: What Is Profits Unlimited?

Profits Unlimited is the newsletter that Paul runs, and he produces only the best information for the financial industry. He teaches clients how to do their best work, and he shares information that he thinks is helpful for the cause. He has 60,000 subscribers, and he will continue to build the newsletter because he has many things to say.

#2: He Believes In Youthful Advancement

Paul Mampilly is very excited about how much youth is in the financial sector. He wants everyone who is young to present their ideas to the industry, and he hopes to see as many of those ideas as possible make it to the masses. He believes that many students need not go to school because they will learn all they need to know from working on Wall Street, and he believes that is what he would have done if he could start over.

#3: He Is A Successful Immigrant

Paul wants all immigrant families to know that they may live the American dream. He has shown quite a lot of class in rising to the top, and he wants to encourage young kids with his background to make a difference in the world. He has talked about this in many writings, and he is open about his pride in being a successful immigrant.

There are many different people who will benefit from learning about and following Paul Mampilly. Paul is a respected investor whose newsletter and large amounts of information will change the narrative on the Wall Street economy. Someone who invests well today will have every chance to make large profits in the future.

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How Mark Autterson Ably Handles His Clients Investment Portfolios

Independent investment management involves an investor using a professional asset manager to manage and guide their portfolio. Most asset managers spread their client’s funds among different asset classes, such as stocks and bonds, so that volatility is reduced and the funds are properly diversified. Depending on the risk tolerance of the client the asset manager will make the portfolio more conservative by tilting more heavily towards bonds or more aggressive by tilting more towards stocks. They can also but some of the funds in other asset classes such as REIT’s or commodities such as gold.

Many types of entities use independent investment managers. This can include individuals as well as pension funds, corporations, educational institutions, nonprofits, and others. In order to provide their services, asset managers charge a fee on the amount of money they are investing for a client, typically 1%.

Mark Autterson is an independent investment manager who is located in Denver, Colorado. He earned his B.S. from Michigan State University in 1979 and soon after joined the financial industry. He is now the Principal Wealth Advisor at his investment company, WIN Wealth Management. Mark Autterson helps his clients calculate their risk profile so that they are comfortable with the way he manages their investments.

WIN offers a 401(k) plan which Mark Autterson is heavily involved in running. He is the go-to person for all of his company’s largest clients due to his expertise and knowledge of investing. Mark Autterson is also the Chief Compliance Officer of the company and is also co-chairs WIN’s investment committee panel.

In his personal life, Mark Autterson is married and has three children along with four grandchildren. He and his family enjoy a broad range of hobbies and activities including outdoor activities like hiking, traveling to new places, and helping out in their local community.


Steps to Buying a Used BMW

When purchasing a BMW, often the first thought is to look for a new car. This is often due to the confusion that surrounds buying a used car. When purchasing a used car it is important that you do thorough research on the dealerships and what they have to offer. Also it is important to research the different types of models available. Also, it is important to research the price of used BMWs to ensure that you are paying a fair price at the dealership.


One of the best dealerships to find a used BMW is the Beverly Hills Auto Group. This luxury used car dealerships offers some of the best in luxury cars. At Beverly Hills Auto Group you can research all the cars that they have available before going in. The Beverly Hills Auto Group offers all customers an opportunity to test drive, their vehicles to ensure quality. For the best in used BMWs search online at the Beverly Hills Auto Group.

Jim Tananbaum ‘s Business is Possible Thanks to Healthcare Needs

The healthcare industry has a lot of needs and a lot of different things that people rely on. Jim Tananbaum knows this and he works constantly to try and make things work the best for the industry and for the people who are a part of the industry. It is something that he has been able to do successfully and something that has made it easier for him to get what he needs out of the different situations. As a private equity firm, Foresite Capital gives healthcare companies the help that they need to be able to be successful. They want to make sure that when a healthcare company wants to start, they are able to start. Jim Tananbaum knows that it is necessary to have the best interest of healthcare patients in mind. He does this so that people will be able to truly enjoy the experience and so that everyone can get what they need out of different situations. Check out his page to know more.

Foresite Capital was born out of a need to make things better. Jim Tananbaum came from the capital and equity industry and saw a lot of healthcare companies unable to get the capital that they needed to get their business started. This was difficult for him and he wanted to show people that things could truly change when they had the capital that they needed. He founded Foresite Capital and chooses to focus the majority of his efforts on making things better for everyone who is a part of the industry.

The healthcare companies can be nearly any size as long as they are emerging in the industry. He caters to small practitioners as much as he does to major healthcare networks. Jim Tananbaum wants to see that healthcare companies have the chance to succeed and he does everything that he can to make it happen. He also wants to help people get the options that they need and to be able to get everything that they can out of the industry. For Jim Tananbaum, helping the healthcare industry is something that just makes the most sense due to his background.

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Fabletics – Finest Quality Atleisure Products at the Most Competitive Rates in the Market

Fabletics is a leading athleisure brand that is giving even Amazon a tough challenge in the online fashion business. Amazon is the market leader in the online fashion retail business with over 20 percent market share, but it seems like Fabletics is going to change that shortly. Fabletics was started as a fashion startup in 2013, but in just four years it has become a stable business with close to $300 million in annual revenue, business operations in over eight countries, and close to 1,500 employees.



Fabletics has become one of the most preferred athleisure brands in the market, and the target audience is women of all age groups. The company offers fitness clothing items from size XXS to 3X, which is unique for any business. It is because the brand aims to inspire people to become healthy and fit and be aware of their body, which is what athleisure apparel is all about.



One of the co-owners of Fabletics is the famous Hollywood actress, Kate Hudson. Kate Hudson is famous among her fan not only for her films and performances but also with her well-toned body and high fitness levels. It is because of this Fabletics brand penetrated the market efficiently and managed to do substantial business from the word go. In short, an association of Kate Hudson with Fabletics has worked wonders for the brand. One other factor that has helped Fabletics tremendously is the use of advanced data analytics technology that allows the management and designers to check what strategies are working, what products are selling more, which business model is earning more revenue, and so on. Technology has helped the brand to capture the target audience’s attention by providing them exactly what they are looking for.


Fabletics also implemented the reverse showroom technique with considerable expertise, just like other famous brands such as Warby Parker and Apple. Once Fabletics had gained substantial momentum in the business and was generating significant revenue, the company aimed at penetrating the market further through opening physical stores. It helped the company to attract new customers, and create awareness about Fabletics. As per the reports, over 35 percent of the women entering the store end up signing up for the company’s VIP membership model. Opening stores helped the company to establish itself as one of the leaders in the fashion business and consolidate its position in the market. Customers looking to experience what Fabletics have to offer regarding value and expertise can take Lifestyle Quiz at its site.

Mr. Jason Halpern – A Renowned Real Estate Developer

Mr. Jason Halpern is a real estate developer. He has complete control of the family business. They have made an investment of $500 million in New York state projects. JMH development is liable for the Townhouses of Cobble Hill project. It has got nine luxury townhouses that are in the Brooklyn area.

Jason Halpern: Born to Develop Property

Mr. Jason Halpern and JMH Development are devoted to making new and creative buildings for the commercial business and rental property all through the New York state area. JMH development is a complete service real estate development firm that has got immense experience as owners or developers of commercial and residential properties all over America.


They adopt a highly creative approach to developing properties in the luxury section. JMG is the beginner in developing the exceptional and nice properties in the finest markets such as Brooklyn, Miami Beach, and Manhattan.

Jason Halpern Real Estate Partner of Aloft Property

JMH’s expert team are renowned in each and every thing of the construction and development process concerning hospitality, residential and other property division. They have got sufficient knowledge of the marketplace and the complete set of development skills. They have got valuable on-site experience. JMH is dedicated to providing exceptional quality properties.


JMH philosophy is known through its concentration on various projects and also for restoring historic properties. JMH Development is headed by Mr. Jason Halpern. The project has been done by the JMH Development and Madden Real Estate Ventures.

Jason Halpern with his Working Mates

The construction is taken care of by the Plaza building, and the architect of the project is ADD, Inc. Aloft South Beach is the finest hotel built in the South Beach since the year 2009. It offers huge rooms that are 360 square feet. The Aloft South Beach will provide a great location that has is accessible to Lake Pancoast and Collins Canal.

The new Aloft will be there in the heart of South Beach which is minutes from Miami Beach convention center and many art galleries and also the Bass Museum of Art. There are many night clubs, boutiques, and restaurants.

Jason Halpern with Model, Milana and Richard

The guest will have fun in the outdoor pool, 24-hour fitness center, and a deck lounge. The hotel will provide free and live access to the coming up local artists and the best bands that have live programming.

Jason’s Family

The Aloft brand offers a great experience and a very modernized style that is varied by design. The Aloft brand provides a great experience and has got a highly modernized form that is modified by design. Starwood Hotels and Resorts Worldwide Inc is the most reputed leisure and hotel companies worldwide and has got at least 1200 properties in one hundred nations. It has got 181,400 employees in its managed properties.

Starwood is an entirely trustworthy owner and franchisor of hotels, residences, and resorts and has got the most reputed brands.